MEMORY – SANKORI

Choline was first identified in 1862 by Adolph Strecker from bile and later recognized as an essential nutrient in the 20th century through studies on liver disease and neural function. In 1998, the Institute of Medicine formally established dietary requirements for choline based on evidence linking deficiency to fatty liver, muscle damage, and impaired cognitive development. Clinically, choline is used to support liver health, lipid metabolism, and prevention of non-alcoholic fatty liver disease. It plays a vital role in acetylcholine synthesis, making it important for memory, cognition, and neuromuscular function. Evidence also supports its use during pregnancy for fetal brain development and neural tube integrity. Emerging research highlights choline’s role in Neurological health through homocysteine metabolism. Rich natural dietary sources of choline include egg yolk (the highest source), liver, red meat, poultry, fish, milk, soybeans, legumes, nuts, whole grains, and cruciferous vegetables such as broccoli and cauliflower.